Association of spermidine plasma levels with brain aging in a population-based study.

Silke M Wortha,Stefan Frenzel,Martin Bahls,Mohamad Habes,Katharina Wittfeld,Sandra Van der Auwera,Robin Bülow,Stephanie Zylla,Nele Friedrich,Matthias Nauck,Henry Völzke,Hans J Grabe,Claudia Schwarz,Agnes Flöel

Alzheimer's & dementia : the journal of the Alzheimer's Association（2022）

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摘要

Elevated spermidine plasma levels are associated with advanced brain aging and might serve as potential early biomarker for AD and vascular brain pathology.

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关键词

Alzheimer's disease,cortical thickness,epidemiology,hippocampal volume,spermidine,white matter hyperintensities

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