Circulating cell-free messenger RNA enables non-invasive pan-tumour monitoring of melanoma therapy independent of the mutational genotype.

Lea Jessica Albrecht, Anna Höwner,Klaus Griewank,Smiths S Lueong,Nils von Neuhoff,Peter A Horn,Antje Sucker,Annette Paschen,Elisabeth Livingstone,Selma Ugurel,Lisa Zimmer,Susanne Horn,Jens T Siveke,Dirk Schadendorf,Renáta Váraljai,Alexander Roesch

Clinical and translational medicine（2022）

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摘要

In sum, we identified a new panel of cfRNAs for a pan-tumour liquid biopsy approach and demonstrated its utility as a prognostic, therapy-monitoring tool independent of the melanoma mutational genotype.

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关键词

biomarker,cell-free RNA,cfRNA,liquid biopsy,melanoma

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