Identification of marker genes to monitor residual iPSCs in iPSC-derived products

Myriam Lemmens,Juliane Perner,Leon Potgeter,Michael Zogg,Sineha Thiruchelvam,Matthias Müller,Thierry Doll, Annick Werner,Yoann Gilbart,Philippe Couttet,Hans-Jörg Martus,Silvana Libertini

Cytotherapy（2023）

引用 6|浏览3

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摘要

Using the example of iCMs, the authors provide a strategy for identifying a set of highly specific and sensitive markers that can be used for quality assessment of iPSC-derived products.

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关键词

Cardiomyocytes,iPSCs,Pre-clinical safety assessment,qPCR,Regenerative cell therapy,Tumorigenicity

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