Cell-derived vesicles from adipose-derived mesenchymal stem cells ameliorate irradiation-induced salivary gland cell damage

Jeong Mi Kim,Mi Eun Choi,Eun Jeong Jeon,Jin-Mi Park,Sungryeal Kim,Jeong Eun Park,Seung Wook Oh,Jeong-Seok Choi

Regenerative Therapy（2022）

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摘要

•ADMSC-CDVs restored the proliferation and amylase activity of SG cells damaged by irradiation.•Reduced TEER in irradiated SG epithelial cells was restored by ADMSC-CDVs.•ADMSC-CDVs have potent radioprotective effects on irradiated SG cells.

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关键词

Salivary gland,Irradiation,Cell-derived vesicles (CDVs),Adipose-derived mesenchymal stem cells (ADMSCs)

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