Novel lncRNA‐prader willi/angelman region RNA, SNRPN neighbour ( PWARSN) aggravates tubular epithelial cell pyroptosis by regulating TXNIP via dual way in diabetic kidney disease

Yi Song,Feng Guo,Yan‐yan Zhao,Xiao‐jun Ma,Li‐na Wu,Ji‐feng Yu,Hong‐fei Ji,Ming‐wei Shao,Feng‐juan Huang,Lin Zhao,Xun‐jie Fan,Ya‐nan Xu,Qing‐zhu Wang,Gui‐jun Qin

Cell Proliferation（2022）

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摘要

These findings illustrate distinct dual molecular mechanisms for PWARSN-modulated TXNIP and PTECs pyroptosis in DKD, presenting PWARSN as a promising therapeutic target for DKD.

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关键词

willi/angelman region lncrna‐prader,tubular epithelial cell pyroptosis,diabetic kidney disease

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