A Systematic Review of The Efficacy and Safety of Ketamine in Total Joint Arthroplasty

Charles P. Hannon,Yale A. Fillingham,Jeremy M. Gililland,Scott M. Sporer,Francisco D. Casambre,Tyler J. Verity,Anne Woznica,Nicole Nelson,William G. Hamilton,Craig J. Della Valle

The Journal of Arthroplasty（2022）

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摘要

High-quality evidence supports the use of ketamine intraoperatively in THA and TKA to reduce postoperative opioid consumption. Most studies found ketamine reduces postoperative pain, nausea, and vomiting. Moderate quality evidence supports the safety of ketamine, but it should be used cautiously in patients at risk for postoperative delirium, such as the elderly.

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关键词

ketamine,multimodal analgesia and anesthesia,total hip arthroplasty,total joint arthroplasty,total knee arthroplasty

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