Hemophilia and Concussion Outcome Study (HeCos): Neurological Status of Children with Hemophilia—Prevalence and Relevance of Mild Traumatic Brain Injury

Background: Mild traumatic brain injury (mTBI) is a common pediatric incident. Despite this, only sparse data exist on the prevalence and consequences of mTBI in patients with hemophilia (PWHs). mTBI itself may impact a child's development, as has been reported for children without hemophilia. Since traumatic injuries, including mTBI, are often well documented for PWHs as incidents leading to factor substitution are generally documented in the patients’ substitution diaries, PWHs could form an interesting and well-documented patient group to study mTBI and its possible consequences.