Does brachytherapy boost improve survival outcomes in Gleason Grade Group 5 patients treated with external beam radiotherapy and androgen deprivation therapy? A systematic review and meta-analysis

Terence Tang,Stephanie Gulstene, Eric McArthur,Andrew Warner,Gabriel Boldt,Vikram Velker,David D'Souza,Glenn Bauman,Lucas C. Mendez

Clinical and Translational Radiation Oncology（2022）

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摘要

•Adding a BT boost to external beam radiation can be used to intensify treatment.•BT boost improves DMFS but not PCSS or OS in Gleason GG5 prostate cancer.•There is no prospective data evaluating BT boost in Gleason GG5 disease.

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关键词

Prostate cancer,Gleason Grade Group 5,External beam radiotherapy,Brachytherapy boost,Survival outcome

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