Systemic and T cell-associated responses to SARS-CoV-2 immunisation in gut inflammation (STAR SIGN study): effects of biologics on vaccination efficacy of the third dose of mRNA vaccines against SARS-CoV-2.

Simon Woelfel, Joel Dütschler, Marius König,Nicole Graf,Vasileios Oikonomou,Claudia Krieger,Samuel Truniger,Annett Franke,Annika Eckhold,Kristina Forsch,Jacqueline Wyss,Niklas Krupka,Werner Albrich,Nicola Frei,Nora Geissler,Peter Schaub,Matthias Friedrich,Benjamin Misselwitz,Wolfgang Korte,Justus J Bürgi,Stephan Brand

Alimentary pharmacology & therapeutics（2023）

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摘要

Anti-TNF-treated IBD patients have impaired humoral and cellular immunogenicity following SARS-CoV-2 booster vaccination. Fourth dose administration may be beneficial for these patients.

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