Impact of GSTT1 and GSTM1 Polymorphisms in the Susceptibility to Philadelphia Negative Chronic Myeloid Leukaemia.

Abozer Y Elderdery,Hadeil M E Idris,Entesar M Tebien,Nada Abdalfatah Diab,Siddiqa M A Hamza,Bandar A Suliman,Abdulaziz H Alhamidi,Nawal Eltayeb Omer,Jeremy Mills

Current cancer drug targets（2023）

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摘要

Our study reveals a strong correlation between GSTT1 polymorphism and Ph-ve CML, whereas the data for GSTM1 polymorphisms indicates no role in the initial development of the disease. More studies are required to further clarify these and other genes' roles in disease development.

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BCR-ABL1,CML,GSTM1,GSTT1,Philadelphia negative and Sudan,null genotype

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