Functional Predictors Discriminating Asthma-COPD Overlap (ACO) from Chronic Obstructive Pulmonary Disease (COPD).

Richard Kraemer,Fabian Gardin, Hans-Jürgen Smith,Florent Baty, Jürg Barandun, Andreas Piecyk,Stefan Minder, Jörg Salomon,Martin Frey,Martin H Brutsche,Heinrich Matthys

International journal of chronic obstructive pulmonary disease(2022)

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摘要
The complexity of COPD with its components of interaction and their heterogeneity, especially in discrimination from ACO, may well be differentiated if patients are explored by a whole set of target parameters evaluating, interactionally, flow limitation, airway dynamics, pulmonary hyperinflation, small airways dysfunction and gas exchange disturbances assessing specific functional deficits.
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关键词
ACO,COPD,COPD and coexisting asthma,LDA,MFA,aerodynamic work of breathing,airway dynamics,linear discriminant analysis,multiple factor analysis,precision medicine,pulmonary hyperinflation,small airways dysfunction
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