Performance of circulating methylated Septin9 gene DNA in diagnosis and recurrence monitoring of colorectal cancer in Western China

Juan-Juan Gao,Ya-Wen Wang,Yang Li,Zhong-Lin Wang,Ai Feng,Na Li,Ling-Yun Hui

Clinica Chimica Acta（2022）

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摘要

•Serum mSEPT9 performed better than traditional markers for CRC detection.•An applicable nomogram was built for predicting the probability of having CRC.•The sensitivity of mSEPT9 was higher than CEA for CRC recurrence monitoring.•The mSEPT9 test should be suggested for FOBT-positive ones or those rejecting FOBT.

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关键词

Methylated Septin9 gene,Diagnosis,Recurrence monitoring,Colorectal cancer,Clinical performance

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