Follistatin Alleviates Hepatic Steatosis in NAFLD via the mTOR Dependent Pathway

Junlu Tong,Li Cong, Yingbin Jia,Bai-Liang He, Yifan Guo,Jianzhong He,Decheng Li,Baojia Zou,Jian Li

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy（2022）

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摘要

Hepatic FST expression increases in NAFLD and plays a protective role in hepatic steatosis. FST overexpression gene therapy alleviates hepatic steatosis via the mTOR pathway.Therefore, gene therapy for FST is a promising treatment in NAFLD.

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follistatin,free fatty acid,lipid synthesis,non-alcoholic fatty liver disease

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