Osteopontin Exacerbates High-Fat Diet-Induced Metabolic Disorders in a Microbiome-Dependent Manner

Jianing Chen,Ping Zeng,Lan Gong,Xujun Zhang,Zongxin Ling,Kefan Bi,Fan Shi,Kaihang Wang,Qiong Zhang,Jingjing Jiang,Yanhui Zhang,Toshimitsu Uede,Emad M. El-Omar,Hongyan Diao

mBio（2022）

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摘要

Gut microbiota are involved in metabolic disorders. However, microbiome-based therapeutic interventions are not always effective, which might be due to interference of the host factors.

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关键词

adhesion,gut microbiome,high-fat diet,metabolic disorder,osteopontin

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