Ketone-Derived 2,3-Dihydroquinazolinones in N-Heteroarene C-H Alkylation via C-C Bond Scission under Oxidative Metal Catalysis

Pinku Prasad Mondal,Amit Pal, Athira K Prakash,Basudev Sahoo

Chemical Communications（2022）

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摘要

A silver-catalysed oxidative sp2 C-H alkylation of N-heteroarenes with ketone-derived 2,3-dihydroquinazolinones at room temperature is developed. The combination of a metal catalyst and perdisulfate oxidant promotes the rarely explored thermal...

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