Seroprevalence and systemic immune biomarkers associated with Toxoplasma gondii infection in blood donors from Southern Brazil

Immunobiology(2022)

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摘要
•High seroprevalence of T. gondii was found in samples of blood donors.•IgM(−)/IgG(+) donors had higher levels of systemic mediators.•IgM(+)/IgG(+) donors were found as high producers of some systemic mediators.•The biomarker signatures may help distinguish between IgM(−) and IgM(+) donors.•Correlation network showed a high connectivity among the mediators in IgM(+)/IgG(+).
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关键词
Toxoplasma gondii,Antibodies,Blood donors,Inflammatory biomarkers
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