Long-Term Clinical Outcomes of Patients with Colorectal Cancer with Metastatic Epidural Spinal Cord Compression Treated with Hybrid Therapy (Surgery Followed by Stereotactic Body Radiation Therapy)

Vikram B Chakravarthy,Ben Schachner,Anubhav Amin,Anne S Reiner,Yoshiya Yamada,Adam Schmitt,Daniel S Higginson,Ilya Laufer,Mark H Bilsky,Ori Barzilai

World Neurosurgery（2023）

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摘要

Hybrid therapy in patients with CRC resulted in 86.7% local control at 2 years after surgery, with limited complications. APC mutations are commonly present in CRC patients with spine metastases and may suggest worse prognosis. Patients with CRC spinal metastases commonly progress outside the index treatment level.

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关键词

Adenomatous polyposis coli gene mutation,Colorectal cancer,Hybrid therapy,Metastatic spinal cord compression,Overall survival,Spine,Spine oncology,Spine radiosurgery

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