Quantitative Microstructural Analysis of Cellular and Tissue Remodeling in Human Glaucoma Optic Nerve Head.

Carolyn Guan,Mary Ellen Pease,Sarah Quillen,Yik Tung Tracy Ling,Ximin Li,Elizabeth Kimball,Thomas V Johnson,Thao D Nguyen,Harry A Quigley

Investigative ophthalmology & visual science（2022）

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摘要

Alteration in LC structure in glaucoma involves migration of astrocytes into axonal bundles, change in astrocyte orientation and processes, production of basement membrane material, and thinning of connective tissue beams.

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关键词

glaucoma, lamina cribrosa, optic nerve head, astrocyte, microglia

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