Study on β-cyclodextrin inclusion technology for volatile oil of Schisandra Chinensis

[Objective] To study the optimum inclusions for volatile oil from Schisandra Chinensis by β-CD. [Methods] To make the oil-bearing, the utilazision ratio of volatile oil from schisandra chinensis and extract ratio of inclusion compound as indicators. To make a comparative test with the methods of trituration method,ultrasound method and saturarated water solution method; to use orthogonal design and select the best packed preparation condition of saturated water soltion method; to examine inclusion compound with microscope method and UV, and observe its stability. [Results] The optimum preparation conditions were estabilished as: β-CD: volatile oil was 1∶10, the inclusion tempereture was 80℃, and inclusion time for 1h.the oil-bearing, the ulilazision ratio of volatile oil from schinensis and extract ratio of inclusion compound were respectively 82.57%, 93.88% and 9.39%. Inclusion compound had the obvious characteristics, its contenta hadn't obviously change and the prepariative stability was strengthened after included. [Conclusions] The optimum β-CD inclusion technology for volatile oil from Schisandra Chinensis was established and provide the basis for the study of inclusion preparation and quality control.