The Molecular Effects of SGLT2i Empagliflozin on the Autophagy Pathway in Diabetes Mellitus Type 2 and Its Complications.

Ranin Saad,Hagar Tadmor,Offir Ertracht,Nakhoul Nakhoul,Farid Nakhoul,Farber Evgeny,Shaul Atar

JOURNAL OF DIABETES RESEARCH（2022）

引用 3|浏览1

暂无评分

摘要

Hyperglycemia reduces LC3-II and ATG5 protein levels which contribute to deficiencies in the autophagy process, with development and progression of DN. SGLT2i significantly reduces progression of DN and onset of end-stage renal disease in T2DM patients, probably through its effect on autophagy.

查看译文

关键词

autophagy pathway,empagliflozin,diabetes mellitus

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要