In vivo assignment of methylmalonic acid in breast tissue using 2D MRS and relationship with breast density, menopausal status and cancer risk.

Gorane Santamaría,Natali Naude,Ian Bennett, Kirby Vosburgh,Sergi Ganau,Xavier Bargalló,Peter Malycha,Carolyn Mountford

NMR in biomedicine（2023）

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摘要

Two tentative assignments are made for MMA in breast tissue of women at elevated risk for cancer. BRCA-mutation carriers exhibited higher values of MMA than those with no known mutation. Premenopausal women with BRCA mutation and dense breasts recorded the highest levels of MMA compared with other categories.

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breast density,in vivo MRS,methylmalonic acid,postmenopause,premenopause

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