Cu‐Catalyzed C−H Perfluoroalkylation/Cyclization of Unactivated Alkenes: Synthesis of Perfluoroalkylated Tricyclimidazoles

A copper‐catalyzed cascade difunctionalization of unactivated olefins with readily available Rf‐I reagents to construct Csp3−CF2/C−C bonds has been reported. This strategy provides a convenient access to a variety of useful perfluoroalkylated tricyclimidazole derivatives in reasonable yields. Preliminary mechanistic studies indicate that the present reaction probably undergo a radical/SET (single electron transfer) pathway. The transformation features mild condition, simple operation, atomic economy, and broad substrate scope.