Association of ATRX mutations with immunologically active characteristics in patients with MSI-prone tumors.

You Ge,Zemin Wang,Han Li,Yangyang Liu,Pingmin Wei

American journal of translational research（2022）

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摘要

Our work found the association of ATRX mutations with immunologically active characteristics in MSI-prone tumors. The combined use of ATRX mutations and MSI-H status might have potential clinical utility for ICIs selection in MSI-prone tumors.

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关键词

ATRX mutations,Immune checkpoint inhibitors,immune activation,microsatellite instability

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