Appendicular dedifferentiated chondrosarcoma: A management and survival study from the SEER database

•Dedifferentiated chondrosarcoma is an aggressive bone tumor with high rates of metastasis that severely impact the patient’s prognosis.•Treatment usually consists of either a limb-salvage procedure or limb amputation, the former being more commonly performed.•Size of the tumor severely impacts the likelihood of presenting metastasis at diagnosis.•Female gender appears to be an important protective factor against death.