Synthesis, in-vitro α-glucosidase inhibition and molecular docking studies of 1,3,4-thiadiazole-5,6-diphenyl-1,2,4-triazine hybrids: Potential leads in the search of new antidiabetic drugs

•1,3,4-Thiadiazole-5,6-diphenyl-triazine hybrids have been synthesized and studied for α-glucosidase inhibition.•Hybrid 7 g was found to be an excellent inhibitor of α-glucosidase (IC50 = 14.36 ± 0.70 µM).•Kinetic analysis shows the mixed mode of inhibition.•The blind docking studies were accomplished to find the binding interactions between synthesized inhibitors and the enzyme.