Effect of chemical modifications of tannins on their antimicrobial and antibiofilm effect against Gram-negative and Gram-positive bacteria.

Xabier Villanueva,Lili Zhen,José Nunez Ares,Thijs Vackier,Heiko Lange,Claudia Crestini,Hans P Steenackers

biorxiv（2022）

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摘要

We were able to modulate the antibiofilm activity of several tannins by specific chemical modifications, providing a first approach for fine tuning of their activity and antibacterial spectrum.

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关键词

Escherichia coli,Pseudomonas aeruginosa,Salmonella Typhimurium,Staphylococcus aureus,antibiofilm activity,structure–activity relationships,tannins

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