Biogenesis of Heneicosane Mediated ZnO Nanoparticles: Characterization and Biological Efficiency

Chemistry Africa(2022)

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摘要
The biogenesis of zinc oxide nanoparticles (ZnO NPs) via the ethyl acetate extract of heneicosane is described in this paper. The absorbing peak of the ZnO NPs was 379 nm, which correlated to the surface plasmon resonance of ZnO NPs. The synthesized ZnO NPs were spherical and had a particle size of less than 25 nm, according to field emission scanning electron microscopy (FE-SEM) and transmission electron microscopy studies. The existence of zinc and oxygen atoms was detected in the energy dispersive X-ray analysis spectrum. The use of atomic force microscopy revealed that the NPs are equally dispersed over the surface. The binding characteristics of biomolecules essential for capping and anchoring the nanoparticles were revealed using Fourier transform infrared spectroscopy. All of the microbial species examined were strongly inhibited by the synthesized ZnO NPs. MTT and NRU studies were used to assess the cytotoxicity of human lung cancer cell lines with IC 50 values of 83.2 and 36.7 µg/mL, respectively. The findings of this investigation suggested that the synthesized ZnO NPs may be exploited as vital biological agents.
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关键词
Biomaterials,Nanoparticles,Nanocomposites,Heneicosane,Cytotoxicity,A549 cell line,Antimicrobial efficiency
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