The impact of obesity on the outcome of severe SARS-CoV-2 ARDS in a high volume ECMO centre: ECMO and corticosteroids support the obesity paradox

M Balik,E Svobodova,M Porizka,M Maly, P Brestovansky, L Volny,T Brozek, T Bartosova, I Jurisinova,Z Mevaldova, O Misovic, A Novotny, J Horejsek,M Otahal,M Flaksa,Z Stach,J Rulisek, P Trachta,J Kolman, R Sachl,J Kunstyr, P Kopecky, S Romaniv,M Huptych,M Svarc, G Hodkova, J Fichtl,F Mlejnsky,T Grus,J Belohlavek,M Lips, J Blaha

Journal of Critical Care(2022)

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摘要
•During the pandemic majority of patients with severe ARDS at a high-volume ECMO centre were obese and morbidly obese.•The rates of ECMO were highest among the morbidly obese (BMI˃40).•The obese patients were cannulated on ECMO after a positive PCR test by two days earlier than the non-obese.•The use of ECMO in the obese patients was not associated with worse outcomes – in contrast to the non-obese patients.•ECMO in obese patients together with the use of steroids in the later stage of ARDS may improve survival.
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关键词
SARS-CoV-2 ARDS,Extracorporeal membrane oxygenation,Covid-19,Obesity,Morbid obesity,Corticosteroids
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