Three-Dimensional Visualization and Quantitative Characterization of Cerebral Microvasculature in Mice

Danny F. Xie,Christian Crouzet,Katiana Khouri,Krystal LoPresti,Yuke Wang,Christopher Robinson,David H. Cribbs,Mark Fisher,Bernard Choi

Biophotonics Congress 2021（2021）

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摘要

We present a method for visualizing cerebral microvasculature in three-dimensions using an exogenous fluorescent label, tissue clearing, and confocal microscopy. A segmentation algorithm was developed for quantitative analysis of microvasculature.

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