Concordance of PGT for aneuploidies between blastocyst biopsies and spent blastocyst culture medium.

Chang Long Xu, Yong Quan Wei,Qing Ying Tan, Ying Huang, Jing Jing Wu,Chun Yuan Li, Ya Feng Ma, Ling Zhou,Bo Liang,Ling Yin Kong,Rui Xia Xu, Ying Ying Wang

Reproductive biomedicine online（2022）

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摘要

The results of niPGT-A of cfDNA of spent BCM are comparable to those of invasive PGT-A of TE biopsies. Modifications of embryo culture conditions and testing methods will help reduce maternal DNA contamination and improve the reliability of niPGT-A.

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关键词

Blastocyst culture medium,Cell-free DNA,Inner cell mass,Non-invasive PGT,Residual blastocyst,Trophectoderm biopsy

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