Blood–Brain Barrier and Brain Structural Changes in Lung Cancer Patients with Non-Brain Metastases

Dafu Zhang,Huan Ma,Zhenhui Li,Guang-Jun Yang,Zhi-Ping Zhang,Yin-Fu He,Mao-Yang Feng,Bao-Ci Shan,Xiufeng Xu,Ying-Ying Ding,Yuqi Cheng

Social Science Research Network（2022）

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摘要

We found an increase in BBB permeability in non-BM aLCs that corresponded to a thinner cortical thickness and smaller subcortical structure volumes. With progression in LC staging, BBB shows higher permeability and may be more likely to develop into BM.

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关键词

blood-brain barrier,brain metastasis,brain structure,dynamic contrast-enhanced MRI,lung cancer

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