Intestinal epithelial cell-specific deletion of cytokine-inducible SH2- containing protein alleviates experimental colitis in ageing mice.

Xiaoming Hu,Fuxin Jiao,Jiali Deng,Ziheng Zhou,Shanghai Chen,Changqin Liu,Zhanju Liu,Feifan Guo

Journal of Crohn's & colitis（2023）

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摘要

CISH might be a proinflammatory regulator in ageing; therefore, targeted therapy against CISH may provide a novel strategy for treating ageing-related IBD.

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关键词

CISH,STAT3,ageing,colitis,oxidative stress

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