Bs-400-04 biochemical effects of catheter-free ventricular ablation with proton beam ablation therapy in normal swine heart

Proton beam therapy has emerged as a promising tool for catheter-free arrhythmia ablation. We previously reported that proton beam lesions become visible in late gadolinium MRI (LGE-MRI) approximately 8 weeks after irradiation. Ablation lesions are also visible in histology; however, the time course of the biochemical changes in these lesions is not yet fully understood.