Po-660-03 optical control of arrhythmia morphology in human induced pluripotent stem cell derived cardiomyocyte cell sheets

Cardiac arrhythmias are a leading cause of mortality, yet current in-vitro models used to investigate cardiac reentry allow for only limited control of arrhythmia parameters and morphology. These criteria are crucial for developing a better understanding of reentrant phenomena, and a technique that permits precise control over these parameters will lead to greater accuracy in modelling cardiac arrhythmias.