Po-686-06 a randomized noninferiority study of the tyrx-a antibacterial envelope alone versus envelope plus intraoperative antibacterial irrigation and postoperative oral antibiotics to prevent cardiac implantable electronic device infections in high-risk patients

Christopher R. Ellis,Suneet Mittal,John A. Andriulli,Paul A. Gould, Roger Carillo, Matthew J. Kolek,Arnold J. Greenspon

Heart Rhythm（2022）

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摘要

CIED infection has a high mortality rate. The WRAP-IT trial showed reduced infection using the TYRX-A envelope. The PADIT trial found no benefit to intensified antibiotic prophylaxis without TYRX-a. This is the first evaluation to test both.

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