3.75 The Association of Childhood Trauma and Psycho-Cardiometabolic Multimorbidity: An Individual Participant Data (IPD) Meta-Analysis

Persons who suffered from childhood trauma seem to be at increased risk of leading unhealthy lifestyles and developing cardiometabolic disease (CMD) and depression. In addition, CMD and depression have been shown to often co-occur. Potentially, early-life stress triggers underlying mechanisms (eg, biological pathways) common to depression and CMD, thus increasing their probability of co-occurrence later in life. This study aims to investigate whether childhood trauma (CM) predicts MDD, CMD, and their co-occurrence (eg, psycho-cardio-metabolic [PCM] multimorbidity) in adulthood.