Tandem Prins bicyclization for the synthesis of tetrahydropyran containing spirocompounds

V. Hanuman Reddy,A. Krishna Kumari,J.K. Lakshmi,Y.V. Rami Reddy,Saikiran Aita,B.V. Subba Reddy

Tetrahedron Letters（2022）

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摘要

•First report on spiroterpenes by Prins bicyclization.•Catalyst is readily available at low cost.•Mild reaction conditions.•High yield and selectivity.

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关键词

Lewis acid,Aldehydes,(±)-Isopulegol,Prins bicyclization,Spirocycles,Octahydro-2H-chromenes

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