Gaita Örneklerinde Helicobacter pylori Antijen Pozitifliği ile İntestinal Parazit Birlikteliğinin Araştırılması

Aim: Helicobacter pylori and intestinal parasitic infections are commonly seen, especially in areas with low socioeconomic status and poor hygiene conditions. H. pylori and Giardia duodenalis can be commonly found in patients with upper gastrointestinal system complaints. It is thought that the urease activity of H. pylori may help intestinal parasites pass into the intestines without being affected by the acidic environment of the stomach. In this study, it was aimed to investigate the association of H. pylori and intestinal parasites (IP) in patients with gastrointestinal system complaints. Material and Method: A total of 408 patients, who were admitted to our hospital with gastrointestinal complaints between 2018 and 2020 and whose H. pylori rapid antigen test was studied simultaneously with intestinal parasite examination in the stool, were evaluated retrospectively. Results: Out of 408 patients whose stool samples were examined, one or more intestinal parasites were detected in 80 (19.6%), and H. pylori antigen test was positive in 65 (15.9%). While there was no statistically significant difference between H. pylori positivity and age groups, the rate of IP detection was found to be significantly higher in children aged 6-18 years. The most prevalent IP was Blastocystis sp. in 74 (18.1%) patients. Intestinal parasite and H. pylori antigen co-positivity in stool samples was detected in eight patients and it was not found statistically significant. Conclusion: H. pylori and intestinal parasites are common all over the world. The relationship between H. pylori and IP is still controversial, and more studies that are comprehensive are needed to understand the association of H. pylori and IP, especially in patients with upper gastrointestinal system complaints.