The effectiveness of nurse-led interventions for cancer symptom management 2000–2018: A systematic review and meta-analysis

•Cancer nurses are concerned with helping patients cope with common symptoms during cancer, either because of the disease itself or its treatment.•Novel nurse-led interventions provide benefit and usually have focused primarily on troublesome symptoms that impact negatively on people’s lives.•Reporting of novel symptom interventions should be strengthened, with outcome measures, duration of effect and component details made clearer.•This meta-analysis demonstrates the importance of new cancer nursing interventions and their contribution to supportive cancer care.