A tandem asymmetric oxidation-oxa-Michael sequence for dearomatization of β-naphthols

A catalytic asymmetric hydroxylative dearomatization reaction has been disclosed,and the products can smoothly transform into spiroannulation adducts by simply treated with a base under mild conditions.Novel in-situ generated magnesium catalytic methods are developed by application of combinational lig-ands.Related concise transformaitons of the spiroannulation adducts have been carried out.