Impact of arginine modified SNARE peptides on interactions with phospholipid bilayers and coiled-coil formation: A molecular dynamics study

•Molecular dynamics study of arginine substituted peptides for coiled-coil complex formation.•Increased affinity of SNARE peptides to the membrane by arginine residues.•Inducing membrane curvature by arginine modified SNARE peptides.•Interaction of docked arginine modified SNARE peptide on membrane with membrane non-interacting SNARE peptide.•Potential enhancement of fusion efficiency