Neurochemical Correlates of Cognitive Functions in Euthymic Patients With Bipolar Disorder: 1H-MRS Study

•Brain MRS in left DLPFC and left hippocampus in euthymic patients with bipolar disorder (BD) shows abnormalities in neurochemical levels.•In BD, ↓ tNAA levels in DLPFC and hippocampus, ↓ glutamate levels in hippocampus and ↑ Inositol and glutamine levels in hippocampus.•In BD, tNAA and glutamate levels in DLPFC correlate with TMT A & B and several subscales of WCST and WMS-III.•In BD, tNAA concentration in hippocampus correlates with subscales of WMS-III.•In BD, neurochemical levels correlate significantly with the extent of cognitive dysfunction even in euthymic phase.