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Structure-based Design, Synthesis and Evaluation of a Novel Family of PEX5-PEX14 Interaction Inhibitors Against Trypanosoma.

Valeria Napolitano,Piotr Mroz,Monika Marciniak,Vishal C. Kalel,Charlotte A. Softley,Julian D. Janna Olmos,Bettina G. Tippler,Kenji Schorpp, Sarah Rioton,Tony Froehlich,Oliver Plettenburg,Kamyar Hadian,Ralf Erdmann,Michael Sattler,Grzegorz M. Popowicz,Maciej Dawidowski,Grzegorz Dubin

European Journal of Medicinal Chemistry（2022）

引用 4|浏览24
关键词
Structure -based drug design,HTS,PPI inhibition,Human African trypanosomiasis,Chagas disease,Glycosomal protein import
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