Bioactive compounds in tea: Effect of imbalanced intake on digestive enzymes activity, cytochrome inhibition and drug interaction

•Chemical and biological characteristics of proteins and polyphenols result in changes in the properties of each other as well as health functionality.•Polyphenols-protein complexes cause the poor function of digestive enzymes.•tea consumption may interfere with the oral bioavailability or activity of some drugs through CYPs inhibition.