Integrated single-cell analysis based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis.

Alma Zernecke,Florian Erhard,Tobias Weinberger,Christian Schulz,Klaus Ley,Antoine Emmanuel Saliba,Clément Cochain

Cardiovascular research（2022）

引用 8|浏览10

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摘要

We refined the nomenclature of mononuclear phagocytes in mouse atherosclerotic vessels, and show conserved transcriptomics features of macrophages and dendritic cells in atherosclerosis in mice and humans, emphasizing the relevance of mouse models to study mononuclear phagocytes in atherosclerosis.

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关键词

atherosclerosis,macrophage,single-cell RNA-seq

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