Case Report: Treatment for steroid-refractory immune-related myocarditis with tofacitinib.

Frontiers in immunology(2022)

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摘要
The safety and efficacy of tofacitinib in a patient with steroid-refractory immune-related myocarditis were investigated, hoping to provide a basis for prospective therapeutic strategies. Tofacitinib led to remarkable remissions in primary autoimmune disease by blocking the inflammatory cascade, indicating its potential therapeutic use in immune-related adverse events.
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关键词
immune checkpoint inhibitors,immunosuppression,myocarditis,steroid-refractory,tofacitinib
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