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Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation

Mashhood A Sheikh,Kevin S O'Connell,Tove Lekva,Attila Szabo,Ibrahim A Akkouh,Jordi Requena Osete,Ingrid Agartz,John A Engh,Dimitrios Andreou,Birgitte Boye,Erlend Bøen,Torbjørn Elvsåshagen,Sigrun Hope,Maren Caroline Frogner Werner,Inge Joa,Erik Johnsen,Rune A Kroken,Trine Vik Lagerberg,Ingrid Melle,Ole Kristian Drange,Gunnar Morken,Terje Nærland, Kjetil Sørensen,Arne E Vaaler,Melissa Authen Weibell,Lars T Westlye,Pål Aukrust,Srdjan Djurovic,Nils Eiel Steen,Ole A Andreassen,Thor Ueland

Biological Psychiatry（2023）

引用 13|浏览45
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摘要
Our results support a systemic and cerebral dysregulation of soluble ICAM-1 expression in SMI and especially in patients with SCZ.
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关键词
Affective disorder,Blood-brain barrier,Cell adhesion molecule,Immune activation,Inflammation,Schizophrenia
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