Vaccine Effectiveness against SARS-CoV-2 Variants in Adolescents from 15 to 90 Days after Second Dose: A Population-Based Test-Negative Case-Control Study.

Eduardo A Oliveira,Maria Christina L Oliveira,Enrico A Colosimo,Ana Cristina Simões E Silva,Robert H Mak,Mariana A Vasconcelos,Ludmila R Silva,Daniella B Martelli,Clara C Pinhati,Hercílio Martelli-Júnior

The Journal of pediatrics（2023）

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摘要

Among adolescents, the VE against all end points was substantially reduced during the omicron-predominant period. Our findings suggest that the 2-dose regimen may be insufficient for SARS-CoV-2 variants and support the need for updated vaccines to provide better protection against severe COVID-19.

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关键词

COVID-19,SARS-CoV-2 variants,adolescents,omicron,vaccine

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