Single-Cell Transcriptome Analysis of Treg.

Benjy Jek Yang Tan,Masahiro Ono,Yorifumi Satou

Methods in molecular biology (Clifton, N.J.)（2023）

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摘要

Regulatory T-cells (Treg) are considerably heterogeneous. Thymically derived Treg (tTreg) are those, which differentiate in the thymus, while peripherally derived Treg (pTreg) differentiate from peripheral mature CD4 T-cells. These two populations are often identified using markers such as neuropilin-1 and Helios (for tTreg) and ROR-γt (for pTreg) in intestines (Tanoue et al., Nat Rev Immunol 16:295-309, 2016).

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关键词

Single-cell RNA-seq (scRNA-seq),Transcriptome,Treg

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