Psycho-socio-clinical profiles and quality of life in seizure disorders: A cross-sectional registry study

•For different seizure disorders, the impairment of quality of life is comparable.•Patients with seizure disorders share a psycho-socio-clinical burden.•Patterns of psycho-socio-clinical burden differ depending on the seizure disorder.•Psycho-socio-clinical variables predict quality of life in patients with epilepsy.•Depressive symptoms predict quality of life in psychogenic nonepileptic seizures.